Cyclosporine and fedratinib combination therapy via modulating Th17/Treg balance in Rat model of membranous glomerulonephritis
Ali Ghassabi, Maryam Hosseini, Hemayat Abdoli Goungormaz, Mohammad Sadegh Soltani-Zangbar, Mahsa Beomidehagh, Davoud Rostamzadeh, Mohammadbagher Pirouzpanah, Arshad Ghaffari-Nasab, Arash Khaki, Leili Aghebati-Maleki, Elham Badihi, Farshid Afandideh, Reihane Shahabirad, Ali Akbar Shekarchi, Javad Ahm · 2024
Read Cyclosporine and fedratinib combination therapy via modulating Th17/Treg balance in Rat model of membranous glomerulonephritis by Ali Ghassabi, Maryam Hosseini, Hemayat Abdoli Goungormaz, Mohammad Sadegh Soltani-Zangbar, Mahsa Beomidehagh, Davoud Rostamzadeh, Mohammadbagher Pirouzpanah, Arshad Ghaffari-Nasab, Arash Khaki, Leili Aghebati-Maleki, Elham Badihi, Farshid Afandideh, Reihane Shahabirad, Ali Akbar Shekarchi, Javad Ahm (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11626047.txt.
Description
Ali Ghassabi and co-authors test a paired drug plan in rats in a 2024 study of a kidney ill. The ill swells the kidney filters as the body shields turn on the self. Two arms of that shield, one that stirs attack and one that calms it, fall out of step in the ill.
Rats were made ill with a shot, then split into groups that got one drug, the other, both, or none. Blood tests and spleen cell reads tracked the shield arms. The pair aims to right the balance better than each drug alone. Such rat work can shape dose picks before human trials are weighed.
Catalog record
| CREATOR | Ali Ghassabi, Maryam Hosseini, Hemayat Abdoli Goungormaz, Mohammad Sadegh Soltani-Zangbar, Mahsa Beomidehagh, Davoud Rostamzadeh, Mohammadbagher Pirouzpanah, Arshad Ghaffari-Nasab, Arash Khaki, Leili Aghebati-Maleki, Elham Badihi, Farshid Afandideh, Reihane Shahabirad, Ali Akbar Shekarchi, Javad Ahm |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |