Early-life challenge enhances cortisol regulation in zebrafish larvae
Luis A Castillo-Ramírez, Ulrich Herget, Soojin Ryu, Rodrigo J De Marco · 2024
Read Early-life challenge enhances cortisol regulation in zebrafish larvae by Luis A Castillo-Ramírez, Ulrich Herget, Soojin Ryu, Rodrigo J De Marco (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625891.txt.
Description
Castillo-Ramírez, Herget, Ryu, and De Marco published in twenty twenty-four a study of stress hormones in baby zebrafish. Fish larvae have a stress axis much like the human one. The team made five-day-old larvae swim for a long spell as an early challenge. A day later, hormone levels at rest looked normal. Responses to a first new stressor were smaller than usual, though.
When a second stressor came soon after, challenged larvae responded more strongly. That window normally suppresses a fresh response. Challenged larvae also had fewer hormone-related brain cells of three types. Genes for hormone making and breakdown were turned up. The authors read this as early tuning of the stress system. Early challenge seems to balance readiness against protection from over-response.
Catalog record
| CREATOR | Luis A Castillo-Ramírez, Ulrich Herget, Soojin Ryu, Rodrigo J De Marco |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |