Quercetin mitigates iron-induced cell death in chicken granulosa cell
Shuo Wei, Felix Kwame Amevor, Xiaxia Du, Linxiang Li, Zhixin Yi, Gang Shu, Yan Wang, Xiaoling Zhao · 2024
Read Quercetin mitigates iron-induced cell death in chicken granulosa cell by Shuo Wei, Felix Kwame Amevor, Xiaxia Du, Linxiang Li, Zhixin Yi, Gang Shu, Yan Wang, Xiaoling Zhao (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625408.txt.
Description
Shuo Wei and co-authors fed a plant pigment to protect hen ovaries in two thousand twenty-four. Egg-laying cells die by an iron-driven process as hens age. That process, ferroptosis, marks follicle decline. Quercetin, a common plant compound, fights it elsewhere. Aging hens received it at several feed doses. Egg output rose with the supplement clearly.
Cell culture tests isolated the mechanism. A chemical trigger forced the iron death pathway. Quercetin blunted the damage like the control drug. Gene activity maps showed which pathways shifted. Ovarian tissue in live hens matched the dish results. Longer laying life is the commercial prize. Natural feed additives may deliver it.
Catalog record
| CREATOR | Shuo Wei, Felix Kwame Amevor, Xiaxia Du, Linxiang Li, Zhixin Yi, Gang Shu, Yan Wang, Xiaoling Zhao |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |