A novel nature-inspired ligno-alginate hydrogel coated with Fe3O4/GO for the efficient-sustained release of levodopa
Athira K, B Siva Kumar, S Giridhar Reddy, K Prashanthi, Sanga Kugabalasooriar, Jyothi Kumari Posa · 2024
Read A novel nature-inspired ligno-alginate hydrogel coated with Fe3O4/GO for the efficient-sustained release of levodopa by Athira K, B Siva Kumar, S Giridhar Reddy, K Prashanthi, Sanga Kugabalasooriar, Jyothi Kumari Posa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625254.txt.
Description
Athira K and co-authors built a plant-based gel that drips out a Parkinson's drug slowly, in a 2024 study. The drug, levodopa, works well but absorbs poorly and wears off fast when swallowed plain. Their gel joins seaweed alginate with a wood-derived acid, set into films and coated with iron oxide and graphene oxide specks.
Two recipes stood out for steady release. One loaded the drug best, at sixty-nine percent, and let out about a quarter of it over forty-eight hours. The graphene coat slowed swelling, which stretched the release. The iron specks made the carrier answer to magnets, a route to guided delivery. Full checks of the films backed their build.
Catalog record
| CREATOR | Athira K, B Siva Kumar, S Giridhar Reddy, K Prashanthi, Sanga Kugabalasooriar, Jyothi Kumari Posa |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |