Effectiveness and Efficiency Comparison of One-Day vs Eight-Day Methotrexate Protocols in Managing Low-Risk Gestational Trophoblastic Neoplasia

Vidiatma Agbari, Yudi Mulyana Hidayat, Andi Kurniadi, Siti Salima, Ali B Harsono, Dodi Suardi, Hariadi Yuseran, Desy Lisnasari · 2024

Read Effectiveness and Efficiency Comparison of One-Day vs Eight-Day Methotrexate Protocols in Managing Low-Risk Gestational Trophoblastic Neoplasia by Vidiatma Agbari, Yudi Mulyana Hidayat, Andi Kurniadi, Siti Salima, Ali B Harsono, Dodi Suardi, Hariadi Yuseran, Desy Lisnasari (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625181.txt.

Description

Agbari and seven co-authors compared two drug schedules in twenty twenty-four for a low-risk cancer that can grow after a molar pregnancy, treated at a hospital in Bandung, Indonesia. Both schedules use the drug methotrexate, but one packs the dose into a single day while the other spreads smaller doses across eight days.

The team reviewed patients treated from twenty twenty to twenty twenty-three. The one-day schedule cleared the disease just as well as the eight-day schedule. It also needed fewer rounds of treatment, caused milder side effects, and cost less. Cost matters here because insurance limits in Indonesia had squeezed the longer schedule. The authors conclude the one-day plan is a sound option for this low-risk group. Their result may help other centers facing the same budget pressure.

Catalog record

CREATORVidiatma Agbari, Yudi Mulyana Hidayat, Andi Kurniadi, Siti Salima, Ali B Harsono, Dodi Suardi, Hariadi Yuseran, Desy Lisnasari
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11625181

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