A case of acute functional hemispherotomy in a young woman with hemimegalencephaly and super-refractory status epilepticus

Kjell Heuser, Louis Romundstad, Jugoslav Ivanovic, Arild Egge, Erik Sætre, Kristin Alfstad, Line Sveberg, Line Bedos Ulvin, Erik Taubøll · 2024

Read A case of acute functional hemispherotomy in a young woman with hemimegalencephaly and super-refractory status epilepticus by Kjell Heuser, Louis Romundstad, Jugoslav Ivanovic, Arild Egge, Erik Sætre, Kristin Alfstad, Line Sveberg, Line Bedos Ulvin, Erik Taubøll (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625172.txt.

Description

Kjell Heuser and eight co-authors report emergency brain surgery that ended eight weeks of nonstop seizures in a young woman. Their 2024 case report concerns a 21-year-old with an oversized left brain half, a birth condition called hemimegalencephaly. Her seizure state resisted every standard rescue: many anti-seizure drugs, anesthetics, steroids, an immune drug, magnesium, and a ketogenic diet.

Brain scans and EEG pointed to the left side as the source. With all other options spent, the team chose a functional hemispherotomy, a surgery that disconnects the faulty half from the rest of the brain. She recovered with manageable deficits and a fair quality of life. The authors believe this is the first such acute operation reported in an adult with her condition. The case widens the options when seizures will not stop.

Catalog record

CREATORKjell Heuser, Louis Romundstad, Jugoslav Ivanovic, Arild Egge, Erik Sætre, Kristin Alfstad, Line Sveberg, Line Bedos Ulvin, Erik Taubøll
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE16 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11625172

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