Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond
Khadija Sarwer, Saeeda Lashari, Nida Rafaqat, Maher, Abdul Raheem, Muneeb Ur Rehman, Syed Muhammad Iraj Abbas · 2024
Read Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond by Khadija Sarwer, Saeeda Lashari, Nida Rafaqat, Maher, Abdul Raheem, Muneeb Ur Rehman, Syed Muhammad Iraj Abbas (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11625047.txt.
Description
Khadija Sarwer and co-authors review a thickened-heart illness that blocks blood outflow, from its genes to new drugs. Their 2024 review covers obstructive hypertrophic cardiomyopathy. Faults in muscle protein genes drive excess growth, stiff filling, and poor blood flow in the heart muscle.
Imaging with sound and magnetic scans remains the main way to grade thickness and blockage. Standard drugs such as beta blockers ease symptoms but do not change the disease course, and results vary by patient. New heart myosin blockers, two of which the review names in depth, mark a shift in care. The authors weigh a combined plan that joins gene insight, imaging, and layered drug therapy.
Catalog record
| CREATOR | Khadija Sarwer, Saeeda Lashari, Nida Rafaqat, Maher, Abdul Raheem, Muneeb Ur Rehman, Syed Muhammad Iraj Abbas |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 85 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |