Differential predictive value of resident memory CD8+T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy
Léa Paolini, Thi Tran, Stéphanie Corgnac, Jean-Philippe Villemin, Marie Wislez, Jennifer Arrondeau, Ludger Johannes, Jonathan Ulmer, Louis-Victorien Vieillard, Joséphine Pineau, Alain Gey, Valentin Quiniou, Pierre Barennes, Hang Phuong Pham, Nadège Gruel, Milena Hasan, Valentina Libri, Sebastien Mel · 2024
Read Differential predictive value of resident memory CD8+T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy by Léa Paolini, Thi Tran, Stéphanie Corgnac, Jean-Philippe Villemin, Marie Wislez, Jennifer Arrondeau, Ludger Johannes, Jonathan Ulmer, Louis-Victorien Vieillard, Joséphine Pineau, Alain Gey, Valentin Quiniou, Pierre Barennes, Hang Phuong Pham, Nadège Gruel, Milena Hasan, Valentina Libri, Sebastien Mel (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11624836.txt.
Description
Léa Paolini and co-authors study immune cells in lung tumors in a 2024 paper. The cells are resident memory T cells, which stay in tissue and guard it. High counts of these cells in tumors track with better results from immune therapy.
Most past work marks these cells by one tag, CD103, yet some lack that tag and carry others. The team used multi-tag cell tests in mice and in fresh human lung tumor samples. They also read the cell receptor sets of each subgroup. The goal is to learn which subgroups do the work and which best predict who gains from therapy. One tag alone may hide the split.
Catalog record
| CREATOR | Léa Paolini, Thi Tran, Stéphanie Corgnac, Jean-Philippe Villemin, Marie Wislez, Jennifer Arrondeau, Ludger Johannes, Jonathan Ulmer, Louis-Victorien Vieillard, Joséphine Pineau, Alain Gey, Valentin Quiniou, Pierre Barennes, Hang Phuong Pham, Nadège Gruel, Milena Hasan, Valentina Libri, Sebastien Mel |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |