Neurodegeneration in the cortical sulcus is a feature of chronic traumatic encephalopathy and associated with repetitive head impacts
Raymond Nicks, Arsal Shah, Spiro Anthony Stathas, Daniel Kirsch, Sarah M Horowitz, Nicole Saltiel, Samantha M Calderazzo, Morgane L M D Butler, Kerry A Cormier, Nurgul Aytan, Fatima Tu-Zahra, Rebecca Mathias, Farwa Faheem, Suzie Marcus, Elizabeth Spurlock, Lucas Fishbein, Camille D Esnault, Alexandr · 2024
Read Neurodegeneration in the cortical sulcus is a feature of chronic traumatic encephalopathy and associated with repetitive head impacts by Raymond Nicks, Arsal Shah, Spiro Anthony Stathas, Daniel Kirsch, Sarah M Horowitz, Nicole Saltiel, Samantha M Calderazzo, Morgane L M D Butler, Kerry A Cormier, Nurgul Aytan, Fatima Tu-Zahra, Rebecca Mathias, Farwa Faheem, Suzie Marcus, Elizabeth Spurlock, Lucas Fishbein, Camille D Esnault, Alexandr (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11624223.txt.
Description
Raymond Nicks and co-authors measure brain cell loss in a brain disease tied to repeated head hits, in work from twenty twenty-four. The disease, chronic traumatic encephalopathy, shows a key protein clump deep in the folds of the brain. Hard numbers on cell loss by brain region had not been reported.
The team studied brain tissue from contact sport athletes and from non athlete controls. Cortex was thinner and nerve cells were fewer deep in the folds in the disease group. Years of play linked strongly to both thinning and cell loss in that zone. Part of the cell loss ran through the protein clumps, while thinning mostly did not. The work pins the worst damage to the fold depths.
Catalog record
| CREATOR | Raymond Nicks, Arsal Shah, Spiro Anthony Stathas, Daniel Kirsch, Sarah M Horowitz, Nicole Saltiel, Samantha M Calderazzo, Morgane L M D Butler, Kerry A Cormier, Nurgul Aytan, Fatima Tu-Zahra, Rebecca Mathias, Farwa Faheem, Suzie Marcus, Elizabeth Spurlock, Lucas Fishbein, Camille D Esnault, Alexandr |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |