Using magnetic resonance relaxometry to evaluate the safety and quality of induced pluripotent stem cell-derived spinal cord progenitor cells
Jerome Tan, Jiahui Chen, Daniel Roxby, Wai Hon Chooi, Tan Dai Nguyen, Shi Yan Ng, Jongyoon Han, Sing Yian Chew · 2024
Read Using magnetic resonance relaxometry to evaluate the safety and quality of induced pluripotent stem cell-derived spinal cord progenitor cells by Jerome Tan, Jiahui Chen, Daniel Roxby, Wai Hon Chooi, Tan Dai Nguyen, Shi Yan Ng, Jongyoon Han, Sing Yian Chew (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11622678.txt.
Description
Jerome Tan and co-authors used a magnetic scan trick in 2024 to judge the quality of lab-grown spinal cord starter cells. Such cells, made from reprogrammed body cells, could one day replace tissue lost to cord injury. Batches vary, though, and standard checks are slow, costly, and destroy the sample.
Their method reads how fast a magnetic signal fades, which tracks iron inside the cells. Starter cells and their parent cells gave clearly different readings. The scan could count leftover parent cells in a batch and even forecast, from day one readings, how well cells would mature weeks later. Poor batches stood out early. The authors offer the scan as a fast, gentle quality gate for cell factories.
Catalog record
| CREATOR | Jerome Tan, Jiahui Chen, Daniel Roxby, Wai Hon Chooi, Tan Dai Nguyen, Shi Yan Ng, Jongyoon Han, Sing Yian Chew |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |