Low ovarian responders produce more progesterone per follicle than normal and high responders
Alfredo Cortés-Vazquez, Alfredo Leonardo Cortés-Algara, Daniel Moreno-García, Johnny S. Younis · 2024
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Description
Alfredo Cortés-Vazquez and three co-authors ask in 2024 whether women whose ovaries respond weakly to fertility drugs make more progesterone per follicle than other patients. An early progesterone rise near the trigger day can hurt assisted reproduction outcomes. Weak responders get high drug doses and carry aging-related changes, a rich setting for the rise.
Records from one Mexico City center span 2015 to 2020. A progesterone-to-follicle index is tested against raw progesterone on trigger day. The index tracks trigger-day levels best among the measures tried. Group contrasts by response type follow, with weak responders classed by Bologna criteria. The index may help clinics spot risky rises that raw levels mask in small follicle counts.
Catalog record
| CREATOR | Alfredo Cortés-Vazquez, Alfredo Leonardo Cortés-Algara, Daniel Moreno-García, Johnny S. Younis |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |