Associations between maternal gestational diabetes mellitus and offspring cerebral palsy: a two-sample Mendelian randomization study
Honghao Peng, Yun Shu, Siyu Lu, Qiongli Fan, Yuping Zhang, Li Ming, Zhifeng Wu · 2024
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Description
Honghao Peng and six co-authors test whether diabetes in pregnancy can cause cerebral palsy in the child, in this twenty twenty-four study. Past watch-and-see studies gave mixed answers, and such studies cannot prove cause. The team used genes as a natural experiment instead.
They took gene variants firmly linked to pregnancy diabetes and checked whether those variants also track with cerebral palsy, autism, and epilepsy in children. Data came from large gene study summaries. The method, called Mendelian randomization, helps sort real cause from mere link. The answer matters for early care in pregnancy and for watching children at risk.
Catalog record
| CREATOR | Honghao Peng, Yun Shu, Siyu Lu, Qiongli Fan, Yuping Zhang, Li Ming, Zhifeng Wu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |