Distinct physiological, transcriptomic, and imaging characteristics of asthma-COPD overlap compared to asthma and COPD in smokers
Vrushali D Fangal, Aabida Saferali, Peter J Castaldi, Craig P Hersh, Scott T Weiss · 2024
Read Distinct physiological, transcriptomic, and imaging characteristics of asthma-COPD overlap compared to asthma and COPD in smokers by Vrushali D Fangal, Aabida Saferali, Peter J Castaldi, Craig P Hersh, Scott T Weiss (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11621799.txt.
Description
Vrushali Fangal and co-authors profile the overlap of asthma and COPD in smokers in a 2024 study. In smokers and older adults the two airway diseases can merge, which blurs diagnosis and care. The team compared the overlap group head-on with each disease alone.
Data came from a gene study of 2,453 smokers aged forty-five to eighty with heavy smoking histories. Checks spanned symptoms, lung tests, blood counts, gene activity, and fine CT scans. Overlap patients showed their own mix of function, inflammation, and structure traits. Gene activity patterns also set the group apart. The profile may help doctors name the overlap sooner and treat its drivers, not just its cough.
Catalog record
| CREATOR | Vrushali D Fangal, Aabida Saferali, Peter J Castaldi, Craig P Hersh, Scott T Weiss |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 88 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |