Integrative analysis of a novel immunogenic PANoptosis‑related gene signature in diffuse large B-cell lymphoma for prognostication and therapeutic decision-making

Ming Xu, Ming Ruan, Wenhua Zhu, Jiayue Xu, Ling Lin, Weili Li, Weirong Zhu · 2024

Read Integrative analysis of a novel immunogenic PANoptosis‑related gene signature in diffuse large B-cell lymphoma for prognostication and therapeutic decision-making by Ming Xu, Ming Ruan, Wenhua Zhu, Jiayue Xu, Ling Lin, Weili Li, Weirong Zhu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11621545.txt.

Description

Ming Xu and six co-authors build a gene score for a fast-growing blood cancer in a 2024 study. The score rests on genes tied to a mixed form of cell death that stirs immune attack. Doctors need better ways to guess how each patient will fare and who will gain from immune care.

The team mined shared gene data banks for genes that part sick from sound tissue, then matched them to the death gene set. A trimmed score was built with two checks for true worth. The study also maps immune cells in tumors, gene flaws, and drug response for high- and low-score groups.

Catalog record

CREATORMing Xu, Ming Ruan, Wenhua Zhu, Jiayue Xu, Ling Lin, Weili Li, Weirong Zhu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11621545

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