Research on the innate immune response in transgenic mice following ischemic stroke
Chao Yuan, Yuting Shentu, Qiuhong Ji · 2024
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Description
Chao Yuan, Yuting Shentu, and Qiuhong Ji review mouse models for studying the innate immune response after ischemic stroke, in a 2024 paper. Stroke brings high rates of death, disability, and recurrence, and immune damage shapes much of that harm. The innate immune system is the body's first line of defense, active at every stage after a stroke. Proteins that steer immune cells sit at the center of that response.
Studying fixed compounds in this system calls for mice with targeted gene changes. The review sorts the models into gene deletion and gene overexpression types. It gathers the models that target innate immunity after stroke and weighs their uses. The authors hope the survey will guide new drug work and better clinical care. They also look toward moving these findings into practice.
Catalog record
| CREATOR | Chao Yuan, Yuting Shentu, Qiuhong Ji |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |