Clinical response and on-treatment clinical remission with tezepelumab in a broad population of patients with severe, uncontrolled asthma: results over 2 years from the NAVIGATOR and DESTINATION studies
Michael E. Wechsler, Guy Brusselle, J. Christian Virchow, Arnaud Bourdin, Konstantinos Kostikas, Jean-Pierre Llanos, Stephanie L. Roseti, Christopher S. Ambrose, Gillian Hunter, David J. Jackson, Mario Castro, Njira Lugogo, Ian D. Pavord, Neil Martin, Christopher E. Brightling · 2024
Read Clinical response and on-treatment clinical remission with tezepelumab in a broad population of patients with severe, uncontrolled asthma: results over 2 years from the NAVIGATOR and DESTINATION studies by Michael E. Wechsler, Guy Brusselle, J. Christian Virchow, Arnaud Bourdin, Konstantinos Kostikas, Jean-Pierre Llanos, Stephanie L. Roseti, Christopher S. Ambrose, Gillian Hunter, David J. Jackson, Mario Castro, Njira Lugogo, Ian D. Pavord, Neil Martin, Christopher E. Brightling (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11618813.txt.
Description
Wechsler leads a large team reporting two year results for an asthma biologic, in work from twenty twenty-four. Tezepelumab treats severe, uncontrolled asthma. Trials ask not only whether patients respond, but whether they reach clinical remission: long term disease stability.
Results came from the NAVIGATOR and DESTINATION studies over two years. Proportions of patients who responded, and who reached on treatment remission, were measured in a broad severe asthma population. Remission as a goal changes asthma care from symptom control toward lasting quiet disease. Two year data show whether that ambition is realistic for this drug class.
Catalog record
| CREATOR | Michael E. Wechsler, Guy Brusselle, J. Christian Virchow, Arnaud Bourdin, Konstantinos Kostikas, Jean-Pierre Llanos, Stephanie L. Roseti, Christopher S. Ambrose, Gillian Hunter, David J. Jackson, Mario Castro, Njira Lugogo, Ian D. Pavord, Neil Martin, Christopher E. Brightling |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |