Which is better in the management of chronic subdural hematoma: Irrigation, or no irrigation? A systematic review and meta-analysis of randomized controlled trials

Abdulsalam Mohammed Aleid, Saud Nayef Aldanyowi, Ayat J. Aleid, Awn Abdulmohsen Alessa, Abdulmonem Ali Alhussain, Loai Saleh Albinsaad, Abbas Saleh Al Mutair · 2024

Read Which is better in the management of chronic subdural hematoma: Irrigation, or no irrigation? A systematic review and meta-analysis of randomized controlled trials by Abdulsalam Mohammed Aleid, Saud Nayef Aldanyowi, Ayat J. Aleid, Awn Abdulmohsen Alessa, Abdulmonem Ali Alhussain, Loai Saleh Albinsaad, Abbas Saleh Al Mutair (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11618649.txt.

Description

Chronic subdural hematoma, a slow bleed between the brain and its covering, is common in older people and is treated by draining it through a small skull hole. Surgeons disagree on whether washing out the space during drainage helps. The authors gather all randomized trials on the question in a systematic review and meta-analysis, following standard reporting rules. Four trials with 843 patients meet their criteria, and two reviewers extract the data and rate each trial's quality.

Pooling the trials, irrigation cuts recurrence of the bleed compared with no irrigation, with an odds ratio of 0.66. Death rates do not differ between the groups. Complications at first look similar, but a sensitivity analysis that removes the source of disagreement shows fewer complications with irrigation. The authors support washing out the space in practice, while calling for larger, high-quality trials to confirm the finding and check long-term results.

Catalog record

CREATORAbdulsalam Mohammed Aleid, Saud Nayef Aldanyowi, Ayat J. Aleid, Awn Abdulmohsen Alessa, Abdulmonem Ali Alhussain, Loai Saleh Albinsaad, Abbas Saleh Al Mutair
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11618649

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