Evaluation of the cross-protective effect of VR2332 modified live virus vaccine against a recombinant NADC34-like porcine reproductive and respiratory syndrome virus
Yu Wu, Limiao Lin, Xiaopeng Gao, Jiaying Zheng, Lijuan Yin, Haishen Zhao, Bohua Ren, Lianxiang Wang, Qunhui Li · 2024
Read Evaluation of the cross-protective effect of VR2332 modified live virus vaccine against a recombinant NADC34-like porcine reproductive and respiratory syndrome virus by Yu Wu, Limiao Lin, Xiaopeng Gao, Jiaying Zheng, Lijuan Yin, Haishen Zhao, Bohua Ren, Lianxiang Wang, Qunhui Li (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11618057.txt.
Description
Yu Wu and co-authors test whether a standard pig virus vaccine also shields against a newer recombinant strain sweeping Chinese farms, in a study from 2024. The NADC34-like lineage of the pig reproductive and respiratory syndrome virus mutates fast and mixes with local strains. The team challenged piglets and sows with a recombinant isolate from their own lab.
Vaccinated piglets showed less virus in the blood, less lung damage, and a solid antibody response. In sows, the unvaccinated group lost one animal and saw one abortion, with only a quarter of piglets surviving. The vaccinated sows all carried through, and 76.5 percent of their piglets survived. The authors rate the old vaccine as partly cross-protective and useful for farm planning.
Catalog record
| CREATOR | Yu Wu, Limiao Lin, Xiaopeng Gao, Jiaying Zheng, Lijuan Yin, Haishen Zhao, Bohua Ren, Lianxiang Wang, Qunhui Li |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |