The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress
Yunfeng Luo, Huaide Gao, Jianghua Zhao, Lin Chen, Jianguo Shao, Linling Ju · 2024
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Description
Luo and coauthors study an enzyme that may hold back liver cancer growth. Liver cancer ranks sixth among all cancers worldwide. Enzymes in this family shape many cell processes and cancer paths. Work on this one enzyme in liver cancer is scarce.
The team gauged enzyme levels in tumor tissue and cells. They raised and cut the enzyme in liver cancer lines. Growth and spread tests tracked what changed with each shift. Gene scans hunted partner proteins the enzyme may sway. Stress from oxygen radicals sat at the core of the effect. High enzyme levels slowed tumor cell growth in tests.
Catalog record
| CREATOR | Yunfeng Luo, Huaide Gao, Jianghua Zhao, Lin Chen, Jianguo Shao, Linling Ju |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |