Association of urinary eosinophilic protein X at age 3 years and subsequent persistence of wheezing and asthma diagnosis in adolescence

Iso Precious Oloyede, Anhar Ullah, Clare S. Murray, Sara Fontanella, Angela Simpson, Adnan Custovic · 2024

Read Association of urinary eosinophilic protein X at age 3 years and subsequent persistence of wheezing and asthma diagnosis in adolescence by Iso Precious Oloyede, Anhar Ullah, Clare S. Murray, Sara Fontanella, Angela Simpson, Adnan Custovic (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11616470.txt.

Description

Many toddlers wheeze, yet only some go on to have asthma as teens. Iso Precious Oloyede and co-authors ask whether a urine marker at age three can help predict that path in a 2024 study.

The marker signals activity of a white blood cell type tied to allergy. It was measured in more than nine hundred children from a birth cohort, who were followed to age 16. Children whose wheeze lasted had higher marker levels at age three. The marker alone predicted later asthma about as well as allergy testing did. A model that combined sex, the marker, allergy status, and wheeze did best. Such early clues could help target watchful care.

Catalog record

CREATORIso Precious Oloyede, Anhar Ullah, Clare S. Murray, Sara Fontanella, Angela Simpson, Adnan Custovic
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11616470

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