A liver transplant patient developed renal injury on tacrolimus and experienced worsening renal function and rhabdomyolysis after switching to sirolimus: a case report
Chang Gao, Zhi-Yu Chen, Liang Ma, Shen-Ju Gou · 2024
Read A liver transplant patient developed renal injury on tacrolimus and experienced worsening renal function and rhabdomyolysis after switching to sirolimus: a case report by Chang Gao, Zhi-Yu Chen, Liang Ma, Shen-Ju Gou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11616183.txt.
Description
Chang Gao and co-authors present a 2024 case report on drug harm after a liver transplant. The patient, a man in his fifties, first took a standard immune drug that hurt his kidneys. Doctors swapped it for a second drug, hoping to spare the kidneys.
A month on the new drug, his kidney function kept falling, and muscle breakdown soon followed. Blood tests showed the new drug had built up to high levels. Kidney tissue showed tube damage and vessel harm. Doctors cut the dose, after which muscle markers settled and kidney function slowly came back. Two years later his kidneys had recovered. The authors urge close blood checks for this drug in clinic care.
Catalog record
| CREATOR | Chang Gao, Zhi-Yu Chen, Liang Ma, Shen-Ju Gou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |