An innovative cellular medicine approach via the utilization of novel nanotechnology-based biomechatronic platforms as a label-free biomarker for early melanoma diagnosis

Jassim A Alqabandi, Rhiannon David, Ussama M Abdel-Motal, Rawan O ElAbd, Kamal Youcef-Toumi · 2024

Read An innovative cellular medicine approach via the utilization of novel nanotechnology-based biomechatronic platforms as a label-free biomarker for early melanoma diagnosis by Jassim A Alqabandi, Rhiannon David, Ussama M Abdel-Motal, Rawan O ElAbd, Kamal Youcef-Toumi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11615046.txt.

Description

Jassim Alqabandi, Rhiannon David, Ussama Abdel-Motal, Rawan ElAbd, and Kamal Youcef-Toumi present in a 2024 paper two tiny biomechatronic platforms for early melanoma detection. Cellular medicine studies disease at the single cell level, where cancer begins. Reading a cell's push and pull forces may flag malignancy before lumps form.

Two mini platforms with custom software and electronics were built, modeled, and fabricated for the tests. In vitro runs probe how contractile force and membrane traits interrelate in cancer cells. The aim is a label free biomarker, a physical signature needing no stains or tags. Bridging bench biology with engineering drives the whole design, the authors stress. Early detection at cell level could arrest spread at its start.

Catalog record

CREATORJassim A Alqabandi, Rhiannon David, Ussama M Abdel-Motal, Rawan O ElAbd, Kamal Youcef-Toumi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE204 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11615046

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