Serum creatinine- and cystatin C-based indices are associated with the risk of subsequent sarcopenia: evidence from the China Health and Retirement Longitudinal Study

Xin Ning, Chao Xie, Yaozhong Kong · 2024

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Description

Xin Ning, Chao Xie, and Yaozhong Kong tested blood-based indices as predictors of sarcopenia. Their 2024 study used data from a large Chinese ageing survey. Sarcopenia means low muscle mass plus weak grip or poor physical performance. Blood creatinine and cystatin C have been proposed as stand-in markers for muscle. Their power to predict future risk was unclear.

The team followed 4,527 adults who were free of sarcopenia at baseline. Four indices were computed from the blood markers. Models then assessed how each index related to new sarcopenia four years later. The analysis used flexible curves and logistic regression. Results bear on whether cheap blood tests can flag older adults at risk. Such flags could guide early checks and care.

Catalog record

CREATORXin Ning, Chao Xie, Yaozhong Kong
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11614666

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