An acute microglial metabolic response controls metabolism and improves memory
Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, Sagar Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, John Andrew · 2024
Read An acute microglial metabolic response controls metabolism and improves memory by Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, Sagar Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, John Andrew (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11614388.txt.
Description
Anne Drougard leads a large team on microglia response to high fat diet. Their study from twenty twenty-four deals with brain immune cells called microglia. Chronic high fat feeding drives obesity and insulin faults.
How fat intake first triggers those states was unknown. Fat rise in spinal fluid sparks a wave of microglial change. Their power units activate and split, and fuel use shifts. Effects show across the brain with just hours of the diet. Removing microglia blocked the acute diet effects in mice. The response helps body metabolism and memory at first.
Catalog record
| CREATOR | Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, Sagar Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, John Andrew |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 128 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |