Neutrophil/lymphocyte ratio is increased in the acute phase of schizophrenia and regardless the use and types of antipsychotic drugs
Yali Zheng, Xianqin Zhou, Kai Chen, Zhengchuang Fu, Peng Zhang, Quanfeng Zhu · 2024
Read Neutrophil/lymphocyte ratio is increased in the acute phase of schizophrenia and regardless the use and types of antipsychotic drugs by Yali Zheng, Xianqin Zhou, Kai Chen, Zhengchuang Fu, Peng Zhang, Quanfeng Zhu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11613812.txt.
Description
Yali Zheng and co-authors tested in 2024 whether a simple blood ratio can flag the acute phase of schizophrenia. Six hundred fifty-one people took part: healthy controls, unmedicated and medicated patients in acute episodes, and medicated patients in remission. Three inflammation ratios were computed from routine blood counts.
Only one ratio, neutrophils over lymphocytes, ran high, and only during acute phases. It was raised whether or not patients took antipsychotic drugs, and no drug type changed the picture. In remission it settled back. The ratio also crept up with illness duration and eased with mood stabilizers. The authors nominate it as a cheap, practical marker of acute flare. They note it cannot yet grade severity or guide dosing.
Catalog record
| CREATOR | Yali Zheng, Xianqin Zhou, Kai Chen, Zhengchuang Fu, Peng Zhang, Quanfeng Zhu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |