Effect of emodin on acute lung injury: a meta-analysis of preclinical trials

Lei Liu, Yu Zhang, Xiao-Ren Tang, Guo-Bing Jia, Shan Zhou, Guo-Long Yue, Cheng-Shi He · 2024

Read Effect of emodin on acute lung injury: a meta-analysis of preclinical trials by Lei Liu, Yu Zhang, Xiao-Ren Tang, Guo-Bing Jia, Shan Zhou, Guo-Long Yue, Cheng-Shi He (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11613585.txt.

Description

Lei Liu and colleagues offer a two thousand twenty-four meta-analysis of emodin, a plant compound, in animal models of acute lung injury. Earlier single studies suggested emodin protects injured lungs. Pooling the animal evidence tests how consistent that protection is.

Twenty-one studies from the past decade were combined. Treated animals showed far lower lung injury scores than controls. Lung water content and a white-cell enzyme marker also dropped. Several inflammatory signals fell sharply with treatment. Study quality was graded with an animal-research tool. The pooled case supports clinical interest, while remaining preclinical evidence only.

Catalog record

CREATORLei Liu, Yu Zhang, Xiao-Ren Tang, Guo-Bing Jia, Shan Zhou, Guo-Long Yue, Cheng-Shi He
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11613585

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