Association between alpha blocker use and the risk of fractures in patients with chronic kidney disease: a cohort study
Keisuke Sunohara, Chikao Onogi, Akihito Tanaka, Kazuhiro Furuhashi, Jun Matsumoto, Keita Hattori, Akiko Owaki, Akihisa Kato, Tomohiro Kawazoe, Yu Watanabe, Eri Koshi-Ito, Shoichi Maruyama · 2024
Read Association between alpha blocker use and the risk of fractures in patients with chronic kidney disease: a cohort study by Keisuke Sunohara, Chikao Onogi, Akihito Tanaka, Kazuhiro Furuhashi, Jun Matsumoto, Keita Hattori, Akiko Owaki, Akihisa Kato, Tomohiro Kawazoe, Yu Watanabe, Eri Koshi-Ito, Shoichi Maruyama (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11613485.txt.
Description
Keisuke Sunohara and co-authors published a 2024 study on whether a common blood pressure drug class raises fracture risk in kidney patients. Alpha blockers are often given to people with chronic kidney disease, whose blood pressure can be hard to control. The same drugs are also used for urination problems in men. Reports on their link to fractures had not settled the question.
The team used a huge Japanese insurance claims database covering 2008 to 2021. They compared kidney patients newly started on alpha blockers with those started on other blood pressure drugs. Men and women were analyzed separately. Users were split by why the drug was prescribed: blood pressure, or urination problems. The main outcome was a first hospital stay for a fracture. Statistical weighting balanced the groups before comparison. The study aims to give prescribers a clearer read on a safety worry for a fragile population.
Catalog record
| CREATOR | Keisuke Sunohara, Chikao Onogi, Akihito Tanaka, Kazuhiro Furuhashi, Jun Matsumoto, Keita Hattori, Akiko Owaki, Akihisa Kato, Tomohiro Kawazoe, Yu Watanabe, Eri Koshi-Ito, Shoichi Maruyama |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |