Organomercury oligonucleotide–polydopamine nanoparticle assemblies discriminate between target sequences by Hg(ii)-mediated base pairing†
Tharun K. Kotammagari, Majid Al-Waeel, Jukka Lukkari, Tuomas Lönnberg · 2024
Read Organomercury oligonucleotide–polydopamine nanoparticle assemblies discriminate between target sequences by Hg(ii)-mediated base pairing† by Tharun K. Kotammagari, Majid Al-Waeel, Jukka Lukkari, Tuomas Lönnberg (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11612767.txt.
Description
A fluorescently tagged oligonucleotide hybridization probe incorporating a single 5-mercuricytosine residue was synthesized and found to adsorb on polydopamine nanoparticles much more strongly than its unmetallated counterpart. Hybridization with target sequences led to release of the probe from the nanoparticle to varying degrees depending on the nucleobase opposite to 5-mercuricytosine.
Catalog record
| CREATOR | Tharun K. Kotammagari, Majid Al-Waeel, Jukka Lukkari, Tuomas Lönnberg |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |