Impact of camel milk lactoferrin peptides against breast cancer cells: in silico and in vitro study

Othman Baothman, Ehab M. M. Ali, Hassan Alguridi, Salman Hosawi, Emadeldin Hassan E. Konozy, Isam M. Abu Zeid, Abrar Ahmad, Hisham N. Altayb · 2024

Read Impact of camel milk lactoferrin peptides against breast cancer cells: in silico and in vitro study by Othman Baothman, Ehab M. M. Ali, Hassan Alguridi, Salman Hosawi, Emadeldin Hassan E. Konozy, Isam M. Abu Zeid, Abrar Ahmad, Hisham N. Altayb (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11612555.txt.

Description

Othman Baothman and co-authors test camel milk peptides against breast cancer cells in a 2024 study. Lactoferrin, a milk protein, breaks into fragments with reported anticancer action. Camel milk is a traditional source whose fragments are little studied, so the team combined computer modeling with lab assays.

Candidate peptides were designed and screened in silico for how they might engage cancer targets, then the promising ones faced real breast cancer cells in dishes. The combined approach maps which fragments act, how strongly, and by what likely mechanism. Natural peptides with few side effects are a long shot worth mapping early, and the study supplies leads for refinement.

Catalog record

CREATOROthman Baothman, Ehab M. M. Ali, Hassan Alguridi, Salman Hosawi, Emadeldin Hassan E. Konozy, Isam M. Abu Zeid, Abrar Ahmad, Hisham N. Altayb
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11612555

Browse the full library · About the Tower of Babel