Image-guided optogenetic spatiotemporal tissue patterning using μPatternScope
Sant Kumar, Hannes M Beyer, Mingzhe Chen, Matias D Zurbriggen, Mustafa Khammash · 2024
Read Image-guided optogenetic spatiotemporal tissue patterning using μPatternScope by Sant Kumar, Hannes M Beyer, Mingzhe Chen, Matias D Zurbriggen, Mustafa Khammash (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11612157.txt.
Description
Sant Kumar and co-authors present a scope that paints living cells with light. Their 2024 paper works in tissue engineering, where shaping cell sheets into set forms is a key aim. The tool, called μPatternScope, projects fine light patterns onto samples under a microscope.
The cells used react to light, so lit zones can be switched on or off by design. The team used timed cell death in lit zones to carve two-dimensional shapes from a cell sheet. A feedback mode reads the sheet as it forms and adjusts the light to hold the target shape. The work joins light-based gene control with optics and feedback design in one bench tool.
Catalog record
| CREATOR | Sant Kumar, Hannes M Beyer, Mingzhe Chen, Matias D Zurbriggen, Mustafa Khammash |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |