Current advances on the role of ferroptosis in tumor immune evasion

Changlin Gao, Haoran Zhang, Xianwei Wang · 2024

Read Current advances on the role of ferroptosis in tumor immune evasion by Changlin Gao, Haoran Zhang, Xianwei Wang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11612115.txt.

Description

Changlin Gao, Haoran Zhang, and Xianwei Wang wrote a 2024 review of ferroptosis, an iron-driven form of cell death, and its role in helping tumours hide from the immune system. In ferroptosis, iron piles up and fats in the cell membrane rust out of control until the cell bursts. Checkpoint drugs have transformed cancer care, yet tumours that evade immunity still defeat them.

The review explains how this death pathway plays out inside the tumour's neighbourhood of immune and support cells. Dying cells spill signals that can either rally or calm immune attack. Understanding that traffic, the authors argue, may let doctors pair ferroptosis triggers with checkpoint drugs for stronger results.

Catalog record

CREATORChanglin Gao, Haoran Zhang, Xianwei Wang
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11612115

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