How to improve AML outcomes?
Taner Tan, Sinem Civriz Bozdag · 2024
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Description
Taner Tan and Sinem Civriz Bozdag offer a 2024 review on how to improve outcomes in acute myeloid leukemia, a fast blood cancer. Deeper grasp of the disease biology and its gene landscape has lifted long-term results. New targets have brought therapies that aim to beat the classic drug pair in use since the 1970s.
In 2022, world and consensus bodies revised how the disease is defined, with genes at the center. The leukemia is now seen as a genetically diverse disease. One past study found 5,234 driver mutations across 76 genes or regions, with two or more drivers in 86 percent of patients. The review frames care around that diversity, matching treatment to each patient's gene profile.
Catalog record
| CREATOR | Taner Tan, Sinem Civriz Bozdag |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |