The Efficacy of Liposomal Bupivacaine in Thoracic Surgery: A Systematic Review and Meta-Analysis
Ruisong Gong, Gang Tan, Yuguang Huang · 2024
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Description
Ruisong Gong, Gang Tan, and Yuguang Huang published this review in 2024 on pain relief after chest surgery. Such surgery leaves fierce pain, and poor control breeds complications. Liposomal bupivacaine is a slow-release form of a numbing drug, said to work for up to seventy-two hours. The team pooled studies that pitted it against plain numbing drugs in chest surgery, searching four data banks to late 2023.
Ten studies qualified, most of them look-back designs and two true trials. Across all of them, the slow-release form showed no edge. Opioid use after surgery, pain scores at one and two days, hospital stay, time to first walk, returns, and complications all matched the plain drugs. The authors conclude the pricey form earns no premium in this setting, though they note more true trials would firm the verdict.
Catalog record
| CREATOR | Ruisong Gong, Gang Tan, Yuguang Huang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |