Bioinformatics Screening and Experimental Validation for Deciphering the Immune Signature of Late-Onset Depression
Xinxia Wang, Yao Gao, Dan Wang, Xinzhe Du, Sha Liu · 2024
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Description
Xinxia Wang and four co-authors hunt for immune clues in late onset depression, which starts late in life and often brings worse thought and daily harm, in a study from 2024. Signs point to immune strain as part of the cause.
Using gene data from patients and healthy peers, the team found immune paths turned up and named two key genes with strong test value. Blood cell mixes also shifted, with more of one cell type and fewer of a key guard type. Tests in an animal model backed the gene finds and showed raised swelling signals in blood and brain.
Catalog record
| CREATOR | Xinxia Wang, Yao Gao, Dan Wang, Xinzhe Du, Sha Liu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |