Synergistic effects of neuroprotective drugs with intravenous recombinant tissue plasminogen activator in acute ischemic stroke: A Bayesian network meta-analysis
Chun Dang, Qinxuan Wang, Yijia Zhuang, Qian Li, Yaoheng Lu, Ying Xiong, Li Feng · 2024
Read Synergistic effects of neuroprotective drugs with intravenous recombinant tissue plasminogen activator in acute ischemic stroke: A Bayesian network meta-analysis by Chun Dang, Qinxuan Wang, Yijia Zhuang, Qian Li, Yaoheng Lu, Ying Xiong, Li Feng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11611160.txt.
Description
Chun Dang and co-authors present a 2024 network meta-analysis on pairing brain-protective drugs with clot-busting therapy in acute stroke. The team gathered 70 randomized trials covering over 8,000 patients, comparing drug plus standard thrombolysis mixes against controls on recovery scores and side effects.
Combinations built on edaravone, edaravone dexborneol, a urinary enzyme drug, and butylphthalide ranked at the top for early recovery scores. Several combos beat thrombolysis alone, while a lower clot-buster dose alone had the fewest adverse events. The authors support adding selected protective drugs, while noting the rankings rest on indirect comparisons across many small trials.
Catalog record
| CREATOR | Chun Dang, Qinxuan Wang, Yijia Zhuang, Qian Li, Yaoheng Lu, Ying Xiong, Li Feng |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |