Effect of remote ischemic preconditioning, nicorandil, and trimetazidine in contrast-induced nephropathy: a network meta-analysis of randomized controlled trials

Hanchao Gao, Weilong Li, Chuanchuan Sun, Shiping Zhu, Fanna Liu, Xinhai Zhao, Shaodong Luan, Shengyun Sun, Yeye Yu · 2024

Read Effect of remote ischemic preconditioning, nicorandil, and trimetazidine in contrast-induced nephropathy: a network meta-analysis of randomized controlled trials by Hanchao Gao, Weilong Li, Chuanchuan Sun, Shiping Zhu, Fanna Liu, Xinhai Zhao, Shaodong Luan, Shengyun Sun, Yeye Yu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11610246.txt.

Description

Gao and eight colleagues compare three methods to prevent contrast induced kidney injury in twenty twenty-four. Contrast agents used in imaging can damage the kidneys. The methods are remote ischemic preconditioning, and two drugs, nicorandil and trimetazidine. The team ran a network meta analysis of randomized trials.

All three methods cut injury rates compared with control care, on top of hydration. Ranking scores placed nicorandil first, then trimetazidine, then preconditioning. Direct differences among the three were not significant, however. Benefits held in patients with poor kidney function and in groups with much diabetes. Evidence quality was graded with a standard framework. The authors conclude all three offer renal protection beyond hydration alone.

Catalog record

CREATORHanchao Gao, Weilong Li, Chuanchuan Sun, Shiping Zhu, Fanna Liu, Xinhai Zhao, Shaodong Luan, Shengyun Sun, Yeye Yu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11610246

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