Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098 an open-label randomized comparative effectiveness trial of extended-release buprenorphine versus treatment as usual on post-hospital treatment engagement for hospitalized patients with opioid use

Gavin Bart, Kelly S Barth, Paulette Baukol, Eva Enns, Udi E Ghitza, Jacklyn Harris, Eve Jelstrom, Jane M Liebschutz, Kara M Magane, Delia Voronca, Zoe M Weinstein, P Todd Korthuis · 2024

Read Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098 an open-label randomized comparative effectiveness trial of extended-release buprenorphine versus treatment as usual on post-hospital treatment engagement for hospitalized patients with opioid use by Gavin Bart, Kelly S Barth, Paulette Baukol, Eva Enns, Udi E Ghitza, Jacklyn Harris, Eve Jelstrom, Jane M Liebschutz, Kara M Magane, Delia Voronca, Zoe M Weinstein, P Todd Korthuis (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11610182.txt.

Description

Gavin Bart and colleagues publish the protocol for a trial by lot. It tests if a long-acting buprenorphine injection lifts patient stay in care after a hospital stay for opioid use disorder. Hospital stays for it are on the rise. Hospital addiction services start medications and set up follow-up. But staying in care after discharge is held back when patients can not get medication fast.

The open-label trial matches real-world care at six US hospitals with full addiction services. It takes in patients in hospital not on opioid medication care of late. Usual care can take in any standard medication except the injection. The trial arm can take in any medication in the stay, plus one injection just before discharge. The outcome is engagement thirty-four days after discharge.

Catalog record

CREATORGavin Bart, Kelly S Barth, Paulette Baukol, Eva Enns, Udi E Ghitza, Jacklyn Harris, Eve Jelstrom, Jane M Liebschutz, Kara M Magane, Delia Voronca, Zoe M Weinstein, P Todd Korthuis
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11610182

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