Nomogram for predicting pregnancy-related relapse of myasthenia gravis
Manqiqige Su, Xiaoqing Liu, Zongtai Wu, Jie Song, Xiao Huan, Huahua Zhong, Rui Zhao, Chongbo Zhao, Yali Zhang, Sushan Luo · 2024
Read Nomogram for predicting pregnancy-related relapse of myasthenia gravis by Manqiqige Su, Xiaoqing Liu, Zongtai Wu, Jie Song, Xiao Huan, Huahua Zhong, Rui Zhao, Chongbo Zhao, Yali Zhang, Sushan Luo (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11610150.txt.
Description
Pregnancy can stir up myasthenia gravis, an autoimmune disease that weakens muscles, and flare-ups cluster at predictable times. Manqiqige Su and co-authors study 113 women with the disease who became pregnant at a Shanghai hospital. Just over half of all recorded relapses hit in the first three months of pregnancy. A similar share struck in the three months after delivery or abortion.
Statistical modeling picked out what raised the risk: younger age at delivery, a shorter calm stretch before pregnancy, and an overgrown thymus gland. Having the thymus removed before pregnancy sharply lowered the risk, while skimping on treatment during pregnancy raised it. The team turned these factors into a nomogram, a scoring chart that estimates each woman's relapse chance. The chart predicted well in their checks.
Catalog record
| CREATOR | Manqiqige Su, Xiaoqing Liu, Zongtai Wu, Jie Song, Xiao Huan, Huahua Zhong, Rui Zhao, Chongbo Zhao, Yali Zhang, Sushan Luo |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |