Reorganized brain functional network topology in stable and progressive mild cognitive impairment
Chen Xue, Darui Zheng, Yiming Ruan, Xuan Cao, Xulian Zhang, Wenzhang Qi, Qianqian Yuan, Xuhong Liang, Qingling Huang · 2024
Read Reorganized brain functional network topology in stable and progressive mild cognitive impairment by Chen Xue, Darui Zheng, Yiming Ruan, Xuan Cao, Xulian Zhang, Wenzhang Qi, Qianqian Yuan, Xuhong Liang, Qingling Huang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11609165.txt.
Description
Chen Xue and co-authors map how brain networks rewire in two kinds of mild cognitive impairment, the stage between normal aging and dementia. Some patients stay stable for years, while others progress. Telling them apart early would help care planning, but the brain changes behind the split are not fully mapped.
Using resting brain scans, the team built network maps for both patient groups and healthy controls, then compared their wiring with graph theory. The groups differed in clustering and small-world traits, and in the strength of key hub regions. Links within and between brain modules also differed, with a module in the cerebellum playing an outsized role. Several network measures tracked thinking scores, hinting they could help predict which patients will progress.
Catalog record
| CREATOR | Chen Xue, Darui Zheng, Yiming Ruan, Xuan Cao, Xulian Zhang, Wenzhang Qi, Qianqian Yuan, Xuhong Liang, Qingling Huang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |