T‐cell‐related skin inflammatory flareups with Th1 polarity in a patient with pseudoxanthoma elasticum

Samuel Rocour, Emeline Vinatier, Céline Fassot, Jonathan Dauvé, Agnès Toutain, Sabrina Fronteau, Marine Monnier, Laurence Preisser, Anne Croué, Olivier Le Saux, Alain Morel, Yves Delneste, Ludovic Martin · 2024

Read T‐cell‐related skin inflammatory flareups with Th1 polarity in a patient with pseudoxanthoma elasticum by Samuel Rocour, Emeline Vinatier, Céline Fassot, Jonathan Dauvé, Agnès Toutain, Sabrina Fronteau, Marine Monnier, Laurence Preisser, Anne Croué, Olivier Le Saux, Alain Morel, Yves Delneste, Ludovic Martin (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11608869.txt.

Description

Samuel Rocour and co-authors study a skin flare in a teen with a rare genetic disease, in a 2024 paper. The disease makes tissues rich in elastic fibers harden with calcium. It is classed as a metabolic disorder. Patients at a French center had reported red flare-ups of their skin lesions, but the flares were never studied in depth.

The patient was 13 years old and had a fresh red lesion in the groin area. A skin sample went for tissue study and gene activity reads. The team compared the flare tissue with calmer skin. Their goal was to name the type of immune response at work. They found signs tied to T cells of one class. Knowing the flare's driver may guide care.

Catalog record

CREATORSamuel Rocour, Emeline Vinatier, Céline Fassot, Jonathan Dauvé, Agnès Toutain, Sabrina Fronteau, Marine Monnier, Laurence Preisser, Anne Croué, Olivier Le Saux, Alain Morel, Yves Delneste, Ludovic Martin
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE12 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11608869

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