Xuesanqi ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating MAPK/ERK/JNK pathway
Qiyuan Su, Qian Hu, Songtao Wu, Suqin Yang, Hanwen Su, Zhengjun Zhang, Chengxiu Ling · 2024
Read Xuesanqi ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating MAPK/ERK/JNK pathway by Qiyuan Su, Qian Hu, Songtao Wu, Suqin Yang, Hanwen Su, Zhengjun Zhang, Chengxiu Ling (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11608202.txt.
Description
Qiyuan Su and co-authors test a traditional Chinese medicine called Xuesanqi in mice with colitis in a 2024 study. Colitis inflames the colon, and the plant rhizome was expected to help by fixing gut microbe imbalance and calming signaling paths that drive inflammation.
Mice with induced colitis lost less weight, had less blood in stool, and kept longer colons with treatment. Gut microbe profiles moved back toward normal, and helpful short chain fatty acids rose. A key inflammatory signaling path settled, and proteins that seal the gut lining rose. The results support further study of the remedy.
Catalog record
| CREATOR | Qiyuan Su, Qian Hu, Songtao Wu, Suqin Yang, Hanwen Su, Zhengjun Zhang, Chengxiu Ling |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |