High Expression of ZNF208 Predicts Better Prognosis and Suppresses the Tumorigenesis of Breast Cancer
Jing Wei, Fangzheng Jiao, Xiaoya Wang, Yifan Qiao, Zihan Yuan, Fang Liu, Yan Fang, Yanfang Pan · 2024
Read High Expression of ZNF208 Predicts Better Prognosis and Suppresses the Tumorigenesis of Breast Cancer by Jing Wei, Fangzheng Jiao, Xiaoya Wang, Yifan Qiao, Zihan Yuan, Fang Liu, Yan Fang, Yanfang Pan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11607762.txt.
Description
Jing Wei and co-authors examine a gene called ZNF208 in breast cancer and find it may act as a brake on the disease, in a 2024 study. The gene helps control other genes and has been linked to the length of the caps that protect chromosome ends. Its role in breast tumors was largely unknown.
Using large public data sets and lab checks, the team found the gene dialed down in breast tumors, with low levels tied to worse outcomes. Its control region was also more heavily switched off in tumors. Higher levels went with slower spread and invasion in their analyses. The authors propose the gene as both a warning marker and a possible treatment lead.
Catalog record
| CREATOR | Jing Wei, Fangzheng Jiao, Xiaoya Wang, Yifan Qiao, Zihan Yuan, Fang Liu, Yan Fang, Yanfang Pan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |