Maternal polycystic ovary syndrome and Offspring’s Risk of Cardiovascular diseases in Childhood and Young Adulthood

Fen Yang, Ziliang Wang, Henrik Toft Sørensen, Imre Janszky, Mika Gissler, Wei Yuan, Maohua Miao, Nathalie Roos, Anna-Karin Wikström, Jiong Li, Krisztina D. László · 2024

Read Maternal polycystic ovary syndrome and Offspring’s Risk of Cardiovascular diseases in Childhood and Young Adulthood by Fen Yang, Ziliang Wang, Henrik Toft Sørensen, Imre Janszky, Mika Gissler, Wei Yuan, Maohua Miao, Nathalie Roos, Anna-Karin Wikström, Jiong Li, Krisztina D. László (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11607077.txt.

Description

Fen Yang and ten co-authors follow nearly seven million Scandinavian children to ask whether a mother's polycystic ovary syndrome raises her child's heart disease risk. Their 2024 register study covers births in Denmark and Sweden from 1973 onward, followed for up to 48 years. Children of affected mothers were already known to carry more risk factors; actual disease was the open question.

Offspring of mothers with the syndrome faced higher rates of cardiovascular disease overall and across several subtypes, even after accounting for the mother's related conditions. A cousin comparison, which strips out much shared family background, did not explain the finding away. The authors stop short of claiming the syndrome itself is the cause. If the link replicates, they argue, these children deserve early prevention attention.

Catalog record

CREATORFen Yang, Ziliang Wang, Henrik Toft Sørensen, Imre Janszky, Mika Gissler, Wei Yuan, Maohua Miao, Nathalie Roos, Anna-Karin Wikström, Jiong Li, Krisztina D. László
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE58 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11607077

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