A review of antimicrobial stability testing guidance for outpatient parenteral antimicrobial therapy programmes: is it time for global harmonization of testing frameworks?
Saiyuri Naicker, Jason A Roberts, Vesa Cheng, Suzanne L Parker, R Andrew Seaton, Mark Gilchrist, Fekade B Sime · 2024
Read A review of antimicrobial stability testing guidance for outpatient parenteral antimicrobial therapy programmes: is it time for global harmonization of testing frameworks? by Saiyuri Naicker, Jason A Roberts, Vesa Cheng, Suzanne L Parker, R Andrew Seaton, Mark Gilchrist, Fekade B Sime (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11606649.txt.
Description
Saiyuri Naicker and six co-authors compare world rules for testing antibiotic stability in this 2024 review. The setting is outpatient parenteral antimicrobial therapy, where patients get intravenous antibiotics outside hospital. A drug is only usable if it stays stable in the delivery device, and each region tests that differently.
The review found three main problems. Guidance on testing varies widely between regulators, above all on temperature. Some regions have no outpatient specific guidance at all. Only Britain's health service gives dedicated non-regulatory advice for these programs. Uneven rules limit which antibiotics patients can use at home depending on where they live. The authors call for one global testing framework built on agreed criteria and expert practice.
Catalog record
| CREATOR | Saiyuri Naicker, Jason A Roberts, Vesa Cheng, Suzanne L Parker, R Andrew Seaton, Mark Gilchrist, Fekade B Sime |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |