Differential regulation of magnesium transporters Slc41, Cnnm and Trpm6-7 in the kidney of salmonids may represent evolutionary adaptations to high salinity environments
Marius Takvam, Elsa Denker, Naouel Gharbi, Valentina Tronci, Jelena Kolarevic, Tom Ole Nilsen · 2024
Read Differential regulation of magnesium transporters Slc41, Cnnm and Trpm6-7 in the kidney of salmonids may represent evolutionary adaptations to high salinity environments by Marius Takvam, Elsa Denker, Naouel Gharbi, Valentina Tronci, Jelena Kolarevic, Tom Ole Nilsen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11605958.txt.
Description
Marius Takvam and five co-authors present a 2024 study of magnesium control in salmon kidneys as the fish prepare for the sea. Salmon move between fresh water and the ocean, facing huge swings in magnesium around them. The kidney carries much of the balancing work, yet the molecular machinery in salmon was unknown.
The team tracked three transporter families known from mammals during the young salmon's transformation for sea life. All three families were present, and their genes switched on and off in differing patterns as salinity readiness rose. The differing regulation hints at evolved division of labor for salty water. The findings sketch how a migratory fish retunes a basic mineral system.
Catalog record
| CREATOR | Marius Takvam, Elsa Denker, Naouel Gharbi, Valentina Tronci, Jelena Kolarevic, Tom Ole Nilsen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 92 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |