Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications
Hua-Qi Si, Peng Wang, Fei Long, Wei Zhong, Yuan-Dong Meng, Yuan Rong, Xiang-Yu Meng, Fu-Bing Wang · 2024
Read Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications by Hua-Qi Si, Peng Wang, Fei Long, Wei Zhong, Yuan-Dong Meng, Yuan Rong, Xiang-Yu Meng, Fu-Bing Wang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11605934.txt.
Description
Hua-Qi Si and colleagues review nanopore sequencing of free DNA for cancer liquid biopsy, in work from 2024. Liquid biopsy reads tumour traces in blood without cutting tissue from the patient. Older read methods split fragments and skew base counts, which can hide weak tumour signals.
Nanopore tools read long strands fast, at high volume, and without copying steps. Those traits may fix the main flaws that limit older blood test routes. The review sums proof of concept work and clinic facing uses so far. Uses span early screening, diagnosis, and tracking care response over time. Multi signal markers in one blood draw form the long term promise.
Catalog record
| CREATOR | Hua-Qi Si, Peng Wang, Fei Long, Wei Zhong, Yuan-Dong Meng, Yuan Rong, Xiang-Yu Meng, Fu-Bing Wang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |