Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis
Tigabu Munye Aytenew, Worku Necho Asferie, Netsanet Ejigu, Binyam Minuye Birhane, Yenework Mulu Tiruneh, Amare Kassaw, Sintayehu Asnakew, Getasew Legas, Birhanu Mengist Munie, Bekalu Mekonnen Belay, Mengistu Ewunetu, Demewoz Kefale, Solomon Demis Kebede · 2024
Read Virological failure and associated factors among patients receiving anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis by Tigabu Munye Aytenew, Worku Necho Asferie, Netsanet Ejigu, Binyam Minuye Birhane, Yenework Mulu Tiruneh, Amare Kassaw, Sintayehu Asnakew, Getasew Legas, Birhanu Mengist Munie, Bekalu Mekonnen Belay, Mengistu Ewunetu, Demewoz Kefale, Solomon Demis Kebede (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11605831.txt.
Description
Treatment failure on antiretroviral therapy in Ethiopia is pooled by Tigabu Munye Aytenew and co-authors in a 2024 meta-analysis. Virological failure matters because it signals drug resistance risk and onward transmission. Individual Ethiopian studies report varying rates, so a national pooled figure and its associated factors were needed to guide program decisions across a large treatment population.
Dozens of primary studies, covering tens of thousands of patients on therapy, were combined. A random-effects model computed the pooled prevalence of virological failure. Associated factors were extracted as the secondary outcome. Sensitivity and subgroup analyses accompany the headline rate. Readers in HIV program management get one number to plan against, plus the patient and treatment factors that push it up or down in Ethiopian care settings.
Catalog record
| CREATOR | Tigabu Munye Aytenew, Worku Necho Asferie, Netsanet Ejigu, Binyam Minuye Birhane, Yenework Mulu Tiruneh, Amare Kassaw, Sintayehu Asnakew, Getasew Legas, Birhanu Mengist Munie, Bekalu Mekonnen Belay, Mengistu Ewunetu, Demewoz Kefale, Solomon Demis Kebede |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |