Latest update on the use of recombinant growth factors for periodontal regeneration: existing evidence and clinical applications
Anahat Khehra, Takahiko Shiba, Chia-Yu Chen, David M Kim · 2024
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Description
Anahat Khehra, Takahiko Shiba, Chia-Yu Chen, and David Kim review, in a 2024 paper, the latest evidence on lab made growth factors for rebuilding gum and bone support around teeth. Growth factors were brought in to make periodontal regeneration more predictable, and they are now widely used in dentistry. Two recombinant factors get the focus here.
One, drawn from platelet signals, draws in ligament and bone cells and makes them multiply. At its best dose, paired with a mineral scaffold, it is approved in several countries for gum regeneration and recession. The other drives wound healing by growing ligament cells and new blood vessels, and is approved in Japan for deep gum defects. Tissue studies show both can yield new bone, cementum, and ligament. Clinical studies report better attachment and defect fill.
Catalog record
| CREATOR | Anahat Khehra, Takahiko Shiba, Chia-Yu Chen, David M Kim |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |