Melanoma in people living with HIV: Immune landscape dynamics and the role of immuno- and antiviral therapies
Lindsay N Barger, Olivia S El Naggar, Binh Ha, Gabriele Romano · 2024
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Description
Lindsay Barger and co-authors review melanoma in people living with HIV in a 2024 paper. This group faces higher melanoma death rates, and the reasons remain partly unclear. Chronic HIV infection leaves viral reservoirs that persist despite therapy, keeping the immune system inflamed and disordered.
The review examines how that immune landscape may create cold tumor surroundings that respond poorly to treatment. It weighs the effects of antiretroviral drugs and the fast-growing field of cancer immunotherapy in this population. Animal models, while imperfect copies of human infection, help reveal the underlying biology. The authors map what is known and what trials most need to answer for safer, tailored care.
Catalog record
| CREATOR | Lindsay N Barger, Olivia S El Naggar, Binh Ha, Gabriele Romano |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |