Liver volumetry improves evaluation of treatment response to hepatic artery infusion chemotherapy in uveal melanoma patients with liver metastases
Sebastian Zensen, Hannah L Steinberg-Vorhoff, Aleksandar Milosevic, Heike Richly, Jens T Siveke, Marcel Opitz, Johannes Haubold, Yan Li, Michael Forsting, Benedikt Michael Schaarschmidt · 2024
Read Liver volumetry improves evaluation of treatment response to hepatic artery infusion chemotherapy in uveal melanoma patients with liver metastases by Sebastian Zensen, Hannah L Steinberg-Vorhoff, Aleksandar Milosevic, Heike Richly, Jens T Siveke, Marcel Opitz, Johannes Haubold, Yan Li, Michael Forsting, Benedikt Michael Schaarschmidt (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11604257.txt.
Description
Sebastian Zensen and co-authors test liver volume measures for judging cancer therapy in a 2024 study. Eye melanoma often spreads to the liver in diffuse patterns. Standard size criteria struggle to score response in such spread. Liver enlargement is common, so volume tracking may help.
The study covered 143 patients treated with liver artery infusion chemotherapy. CT scans before and after therapy fed both scoring methods. Median survival for the group was just over a year. A ten percent volume rise split patients sharply by survival. Those below the threshold lived more than twice as long as those above. Standard criteria failed to separate survival in the same way. Volume was the only significant prognostic factor in their models. The authors recommend liver volumetry for response checks. Earlier switches of failing therapy could follow.
Catalog record
| CREATOR | Sebastian Zensen, Hannah L Steinberg-Vorhoff, Aleksandar Milosevic, Heike Richly, Jens T Siveke, Marcel Opitz, Johannes Haubold, Yan Li, Michael Forsting, Benedikt Michael Schaarschmidt |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |